Anti-pro-caspase-3抗體,半胱天冬酶-3酶原抗體*產品詳細資料

產品編號 BYK-2593R

英文名稱 Caspase 3 precursor
中文名稱 半胱天冬酶-3酶原抗體
別    名 Caspase 3 precursor; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.
研究領域 細胞生物  神經生物學  信號轉導  細胞凋亡  
分 子 量 28kDa

抗體來源 Mouse or Rabbit
克隆類型 Monoclonal or Polyclonal
產品應用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此產品應用不做依據，具體產品應用與實驗稀釋比請！

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
亞    型 IgG
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-pro-caspase-3抗體,半胱天冬酶-3酶原抗體*產品介紹 

      Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Gene for Caspase 3 also known as Yama, CPP32, and apopain codes for a 32-kDa protein. Caspase 3 cleaves the death substrate poly(ADP-ribose) polymerase (PARP) to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other Caspase 3 substrates include DNA-PK, actin, GAS2, and procaspase-6, etc. Caspase 3 is activated by cleavage events at Asp-28/Ser-29 (between N-terminal pro-domain) and Asp-175/Ser-176 (between large and small subunits) to generate a large subunit of 17-kDa and a small subunit of 12-kDa.

 此相關標記有：Alexa Fluor 350 標記、Alexa Fluor 488 標記、Alexa Fluor 555 標記、Alexa Fluor 647 標記、AP標記、APC標記、Biotin標記、Cy3標記、Cy5標記、Cy5.5標記、Cy7標記、FITC標記、Gold標記、HRP標記、PE標記、PE-Cy3標記、PE-CY5標記、PE-CY5.5標記、PE-CY7標記、RBITC標記 

    相關產品：

     Anti-GRAP抗體,生長因子受體結合蛋白2相關接頭蛋白抗體

Anti-GRB 14抗體,生長因子受體結合蛋白14抗體
Anti-GAL4抗體,調節蛋白GAL4抗體
Anti-GRO Alpha抗體,黑色素瘤刺激活性蛋白α抗體
Anti-GLUT2抗體,葡萄糖轉運蛋白2抗體
Anti-GADD34抗體,生長抑制DNA損傷基因34抗體
Anti-Galectin-1抗體,半乳糖凝集素1抗體
Anti-GRP抗體,半乳糖凝集素相關蛋白GRP抗體
Anti-Gastrokine 1抗體,胃竇粘膜蛋白GKN1抗體
Anti-GA2L2抗體,GA2L2蛋白抗體
Anti-GABARAPL3抗體,γ氨基丁酸受體相關蛋白樣3抗體
Anti-GABRR3抗體,G氨基丁酸A型受體rho3/GABAc Rρ3抗體
Anti-GAGE1抗體,GAGE1蛋白抗體
Anti-GAGE12H抗體,GAGE12H蛋白抗體
Anti-GAGE2A抗體,GAGE2A蛋白抗體
Anti-GAGE6抗體,GAGE6蛋白抗體
Anti-GAK抗體,細胞周期蛋白G相關激酶抗體
Anti-GAL3ST1抗體,半乳糖神經酰胺磺基轉移酶抗體
Anti-GAL3ST2抗體,半乳糖神經酰胺磺基轉移酶2抗體
Anti-GAL3ST4抗體,GAL3ST4蛋白抗體