Anti-AQP9 antibody熱銷(xiāo)

FROM: Abcam

Catalog Number : BYK-0932R       
Quantity size :   100ug  (0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide)

Anti-AQP9 antibody熱銷(xiāo)Background: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". A new member of AQP family, Aquaporin-9 (AQP9), has been cloned from human leukocytes by homology cloning (Ishibashi et al. 1997). It is mostly homologous with AQP3 and AQP7 (54-48% identity). AQP9 (295 AA) is primarily expressed in peripheral leukocytes, and lesser amounts in liver, lung and spleen. AQP9 is permeable to water and urea. Unlike AQP3 and AQP7, it did not facilitate glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic. A new member of the AQP family, AQP9, has been cloned from human leukocytes. It is homologous with AQP3 and AQP7 (54-48% identity). AQP9 (29a) is primarily expressed in peripheral leukocytes, and in lesser amounts in liver, lung and spleen. AQP9 is permeable to water and urea. Unlike AQP3 and AQP7, it does not facilitate glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic.

Specificity :   

• Anti-AQP9 is a rabbit polyclonal antibody unconjugated                
• specific for AQP9 of Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, GuineaPig          
• use for western blotting,elisa,immunoprecipitation and immunohistochemistry
• Protein G affinity chromatography purification, purity :>95%
• Isotype:  IgG
• molwt:   32kDa

Anti-AQP9 antibody熱銷(xiāo)Application :  

• Western blotting 1:100-500                
• Immunohistochemistry 1:100-500                 
• ELISA 1:500-1000
• IP=1:20-100    Flow-Cyt=1:100-500
• IF=1:100-500                  
• Optimal working dilutions must  be determined by the end user.

Storage:  Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The  lyophilized antibody is stable at room temperature for at least one month and for greater  than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent  of antibody, the antibody is stable for at least six weeks at 2-4 ℃

Anti-AQP9 antibody熱銷(xiāo)Important Note: This product as supplied is intended for research use only, not for use in  human, therapeutic or diagnostic applications.