博研生物抗體，“葡萄糖調節蛋白78抗體,Anti-GRP78/BIP/HSPA5抗體*抗體”應用于IHC、WB、 IF、IP、ELISA，質量保證，無效免費退換，另外本公司生產經營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！

產品介紹：

【產品名稱】：葡萄糖調節蛋白78抗體,Anti-GRP78/BIP/HSPA5抗體*抗體

【產品類型】：一抗

【產品編號】：BYk-1219R                    

【相關標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647

【性 狀】： Lyophilized or Liquid

【濃 度】： 1mg/1ml

【亞 型】： IgG

【規 格】：0.1ml/100ug，0.2ml/200ug

【抗體來源】： Rabbit OR MOUSE

【克隆類型】： polyclonal or monoclonal

【產品用途】：科研實驗，用于免疫組化實驗，WB實驗、IF、IP、ELISA實驗，相應的標記抗體有HRP標記抗體，FITC標記，BIO等。

【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

【信息詳情】： The 78 kDa glucose regulated protein/BiP （GRP78） belongs to the family of ~70 kDa heat shock proteins （HSP 70）. GRP78 is a resident protein of the endoplasmic reticulum （ER） and may associate transiently with a variety of newly synthesized secretory and membrane proteins or permanently with mutant or defective proteins that are incorrectly folded, thus preventing their export from the ER lumen. GRP78 is a highly conserved protein that is essential for cell viability. The highly conserved sequence Lys-Asp-Glu-Leu （KDEL） is present at the C terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 （GRP 94） and protein disulfide isomerase （PDI）. The presence of carboxy terminal KDEL appears to be necessary for retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

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