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胭脂紅號:1390-65-4
英文名稱:Carmine;Alum lake of carminic acid;Cochineal;Nacarat;Natural Red 4 ;7-beta-D-Glucopyranosyl-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-anthracene-2-carboxylic acid
其他名稱:蟲紅;洋紅;卡紅;胭脂蟲紅;7-β-D-吡喃葡萄糖基-3,5,6,8-四羥基-1-甲基-9,10-二氧代-蒽-2-羧酸;胭脂蟲粉;洋紅色淀;洋紅酸色淀
號:1390-65-4
C88H72O52AI2Ca3?4H2O=2206
級別:For microscopy
含量:≥85.0%
性狀(以下信息僅供參考):鮮紅色粉末或片狀物,易磨成粉。系胭脂紅酸的鋁鈣色淀,溶于硼砂液,還溶于堿金屬的氫氧化物或碳酸鹽類成深紅色溶液,部分溶于熱水,幾乎不溶于冷水或稀酸
用途:本品僅供科研,不得用于其它用途。(以下用途僅供參考)胚胎學中作整體染色;細胞核染色;滴定氨溶液指示劑;顯微分析;熒光分析
保存:RT,避光
胭脂紅號:1390-65-4儲存條件:
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋!受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
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存儲:應貯存在干燥清潔避光的環境中,嚴禁與有毒物質混放,以免污染(保質期為兩年)。
胭脂紅號:1390-65-4主要優級純、分級純和化學純3種:
(1)優級純(GR:Guaranteed reagent),又稱一級品或保證試劑,99.8%,這種試劑純度Z高,雜質含量Z低,適合于重要精密的分析工作和科學研究工作,使用綠色瓶簽。
(2)分析純(AR),又稱二級試劑,純度很高,99.7%,略次于優級純,適合于重要分析及一般研究工作,使用紅色瓶簽。
(3)化學純(CP),又稱三級試劑,≥ 99.5%,純度與分析純相差較大,適用于工礦、學校一般分析工作。使用藍色(深藍色)標簽。
(4)實驗試劑(LR:Laboratory reagent),又稱四級試劑。
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Caspr and the closely related Caspr2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. Specifically, Caspr exists at the paranodal junctions, while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region. Caspr may play a role in the communication of glial cells and neurons during development.
Function : Neurexin 2 alpha belongs to the Neurexin family, a group of neuronal proteins that function as cell adhesion molecules during synaptogenesis and intracellular signaling. Mammalian genomes contain just three neurexin genes. However, many neurexin isoforms may be expressed through the use of two alternative promoters and alternative splicing at up to five different positions.
Subunit : The laminin G-like domain 1 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan. Interacts with INADL (By similarity).
Subcellular Location : Membrane; single-pass type I membrane protein.
Tissue Specificity : Predominantly expressed in brain.
Similarity : Belongs to the neurexin family.
Contains 3 EGF-like domains.
Contains 6 laminin G-like domains.
Database links : UniProtKB/Swiss-Prot: Q9P2S2.1
英文名稱 Anti-Neurexin 1
中文名稱 軸突蛋白1(Neurexin 1α)抗體
別 名 Neurexin 1 alpha; Neurexin 1 beta; Neurexin I-alpha; Neurexin-1-alpha; NRX1A_HUMAN; NRXN1; PTHSL2.
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit
產品類型 一抗
研究領域 神經生物學 細胞粘附分子 細胞骨架
蛋白分子量 predicted molecular weight: 159kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Neurexin 1
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Neurexins comprise a family of neuronal cell surface proteins, which include neurexin I (NRXN1), neurexin II (NRXN2), neurexin III (NRXN3) and Caspr (neurexin IV). Neurexins I-III are expressed as a and b isoforms. The a isoforms are made of three cassettes, which contain two LNS (胭脂紅號:1390-65-4Laminin A, Neurexins, Sex hormone-binding)-domains separated by EGF domains, followed by a transmembrane region and a 55 amino acid cytoplasmic C-terminal. The a isoforms bind to neurexophilins at the second LNS site and to the excitatory neurotoxin a-latrotoxin. The b isoforms have only one LNS-domain, bind to neuroligins, and play a role in the formation and remodeling of synapes. Caspr (for Contactin-Associated Protein 1, also designated Paranodin in mouse), contains an extracellular domain similar to the other three neurexins, and binds to the surface glycoprotein Contactin. Caspr and the closely related Caspr2, a mammalian homolog of Drosophila Neurexin IV (Nrx-IV), demarcate distinct subdomains in myelinated axons. Specifically, Caspr exists at the paranodal junctions, while Caspr2 colocalizes with Shaker-like K+ channels in the juxtaparanodal region. Caspr may play a role in the communication of glial cells and neurons during development.
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