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中性紅號：553-24-2   
英文名稱：Neutral red；Toluylene red；Aminodimethylaminotoluaminozine；3-Amino-7-dimethylamino-2-methylphenazine hydrochloride；C.I. 50040     
其他名稱：堿性紅5；2-甲基-3-氨基-6-二甲氨基二氮雜蒽鹽酸鹽；3-氨基-6-二甲氨基-2-甲基吩嗪鹽酸鹽   
號：553-24-2   
C15H17ClN4=288.78    
級別：IND    
pH變色域：6.8（紅色）～8.0（黃色）   
靈敏度試驗：合格   
乙醇溶液試驗：合格   
灼燒殘渣：≤2.0%    
性狀(以下信息僅供參考)：深綠色、棕色或淺黑色粉末。溶解度為水4.0％，無水乙醇1.8％，乙二醇乙迷3.75％，乙二醇3.0％。幾乎不溶于二甲苯，其水溶液或乙醇溶液呈紅色。Z大吸收波長(50％乙醇) 533nm。   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)酸堿指示劑；水、亞硝酸鹽和尿的堿度指示劑；組織化學中用于脂肪的水解指示劑；神經細胞的尼爾(Nissl)小粒染色；與健那綠共用于血液體外活體染色；碘離子的光度測定；中性紅試紙的制備   
保存：RT 
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1
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.
Function : Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing. Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion.
Subunit : Interacts with NRXN1, NRXN2 and NRXN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3). Interacts with INADL. Interacts with GPHN.
Subcellular Location : Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, presynaptic cell membrane. Note=Detected at postsynaptic membranes in brain. Detected at dendritic spines in cultured neurons. Colocalizes with GPHN and ARHGEF9 at neuronal cell membranes (By similarity). Localized at presynaptic membranes in retina. Colocalizes with GABRG2 at inhibitory synapses in the retina.
Tissue Specificity : Expressed in the blood vessel walls. Detected in colon, brian and pancreas islets of Langerhans (at protein level). Detected in brain, and at lower levels in pancreas islet beta cells.
Similarity : Belongs to the type-B carboxylesterase/lipase family.
英文名稱  Anti-NIPAL3
中文名稱  NIPA樣蛋白3抗體
別    名  NPAL3; NPAL-3; NIPA like domain containing 3; NIPA like protein 3; RGD1563439; RP23-332E2.5; RP3-462O23.3; NPAL3_HUMAN.
濃    度  1mg/1ml
規 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應  Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep
中性紅號：553-24-2性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human NIPAL3
亞    型  IgG
純化方法  affinity purified by Protein A
儲 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4