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N-(4-氨基丁基)-N-乙基異魯米諾號:66612-29-1
3,3'5,5'-四甲基聯苯胺丙磺酸鈉號:102062-36-2
N-乙基-N-(3-磺丙基)-3-甲氧基苯胺鈉鹽號:82611-88-
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3',6'-二熒光素號:630-88-6
英文名稱:3',6'-Dichlorofluoran;Fluorescein dichloride
其他名稱:3ˊ,6ˊ-二熒光橙紅;3ˊ,6ˊ-二熒光紅;3ˊ,6ˊ-二熒光黃;3ˊ,6ˊ-二熒烷;化熒光素
號:630-88-6
C20H10Cl2O3=369.2
級別:BR
純度:≥90%
性狀(以下信息僅供參考):橙色粉末。溶于乙醇,不溶于水或酸
用途:本品僅供科研,不得用于其它用途
保存:RT,保質期5年客戶根據3',6'-二熒光素號:630-88-6性質、化學式、分子式、結構式、比重、密度、號、沸點、熔點、水溶性、MSDS、用途、作用、規格包裝、性狀、注意事項、英文名、別稱、純度、級別等情況,本產品化學性質穩定,運輸條件不苛刻,一般儲存在陰涼,干燥,通風良好的地方,遠離不相容的物質。保持容器密閉。
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產品介紹 Component of the cytoplasmic fibrils of the nuclear pore complex implicated in nuclear protein import. Its N-terminus is involved in activation of oncogenic kinases. Plays a role in the mitotic spindle checkpoint.
Function : Component of the cytoplasmic fibrils of the nuclear pore complex implicated in nuclear protein import. Its N-terminus is involved in activation of oncogenic kinases. Plays a role in the mitotic spindle checkpoint.
Subunit : Interacts with MAD1L1 and MAD2L1.
Subcellular Location : Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Chromosome, centromere, kinetochore. Note=The assembly of the NPC is a stepwise process in which Trp-containing peripheral structures assemble after other components, including p62. Detected at kinetochores during prometaphase.
Tissue Specificity : Highest in testis, lung, thymus, spleen and brain, lower levels in heart, liver and kidney.
Post-translational modifications : Phosphorylated upon DNA damage, probably by ATM or ATR.
DISEASE : Defects in TPR are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=Chromosomal aberrations involving TPR are found in thyroid papillary carcinomas. Intrachromosomal rearrangement that links the 5'-end of the TPR gene to the protein kinase domain of NTRK1 forms the fusion protein TRK-T1. TRK-T1 is a 55 kDa protein reacting with antibodies against the carboxy terminus of the NTRK1 protein.
Involved in tumorigenic rearrangements with the MET or RAF genes.
Involvement in disease;Defects in TPR are a cause of thyroid papillary carcinoma (TPC). TPC is a 3',6'-二熒光素號:630-88-6common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=Chromosomal aberrations involving TPR are found in thyroid papillary carcinomas. Intrachromosomal rearrangement that links the 5'-end of the TPR gene to the protein kinase domain of NTRK1 forms the fusion protein TRK-T1. TRK-T1 is a 55 kDa protein reacting with antibodies against the carboxy terminus of the NTRK1 protein. Note=Involved in tumorigenic rearrangements with the MET or RAF genes.
英文名稱 Anti-NR2F2/NR2F1
中文名稱 載脂蛋白AI調節蛋白1抗體
別 名 Apolipoprotein AI regulatory protein 1; ARP1; COUP TF2; COUP transcription factor 2; Chicken ovalbumin upstream promoter 1; COT1_HUMAN; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP-TF1; EAR-3; EAR3; ERBAL3; NR2F1; NR2F2; Nuclear receptor subfamily 2 group F member 1; SVP44; TCFCOUP1; TFCOUP1; Transcription factor COUP 1; V ERBA related protein EAR 3; V-erbA-related protein 3.
濃 度 1mg/1ml
規 格 0.1ml/100μg 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep
產品類型 一抗
研究領域 腫瘤 心血管 細胞生物 免疫學 染色質和核信號 神經生物學 信號轉導 生長因子和激素 細胞分化 表觀遺傳學
蛋白分子量 predicted molecular weight: 46kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human NR2F2.
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
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