赤蘚紅號：16423-68-0   
英文名稱：Tetraiodofluorescein sodium salt；Erythrosin； Sodium tetraiodofluorescein；Iodeosine；Erythrosine BS； Pyrosine B；Dianthine B；Erythrosin B   
其他名稱：藻紅；藻紅B；酸性地衣紅；2′,4′,5′,7′-四碘熒光素二鈉；四碘熒光素二鈉；藻紅B 鈉鹽；赤蘚紅B；潤滑劑X-1；N,N'-亞乙基雙硬脂酰胺；螺異苯并呋喃-1(3H),9’-[9H]占噸-3-酮-3’,6’-二羥基-2’,4’,5’,7’-四碘代二鈉鹽；四碘熒光素B；酸性紅51    
號：16423-68-0或568-63-8   
C20H6I4Na2O5=879.88   
級別：IND   
含量（干品計）：≥80.0%   
靈敏度試驗：合格    
水溶解試驗：合格   
干燥失重：≤8.0%   
性狀(以下信息僅供參考)：棕色粉末。溶于水溶液呈櫻紅色，溶于乙醇。加鹽 酸于水液中析出黃棕色沉淀，加氫氧化鈉生成紅色沉淀，但能溶于過量試劑中。Z大吸收波長(水中)524nm、(95％乙醇中) 531nm。   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)沉淀滴定的吸附指示 劑。酸堿滴定熒光指示劑，pH大于2.5無熒光，pH不小于4.0呈淺綠色熒光。光度測定試劑。生物染色劑   
保存：RT，避光赤蘚紅號：16423-68-0儲存條件：
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
運輸：汽車運輸、EMS郵政快遞，申通快遞等， 款到上海3天內發貨；
售后：如您對我們的產品服務及技術指標有特殊要求，請及時通知我方。
存儲：應貯存在干燥清潔避光的環境中，嚴禁與有毒物質混放，以免污染（保質期為兩年）。
赤蘚紅號：16423-68-0主要優級純、分級純和化學純3種：
（1）優級純（GR：Guaranteed reagent），又稱一級品或保證試劑，99.8%，這種試劑純度Z高，雜質含量Z低，適合于重要精密的分析工作和科學研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級試劑，純度很高，99.7%，略次于優級純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學純（CP），又稱三級試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學校一般分析工作。使用藍色（深藍色）標簽。
（4）實驗試劑（LR：Laboratory reagent），又稱四級試劑。
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coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation and DNA-binding. Interacts with SPAG9 and UNC5CL.
Function : This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
Subunit : Component of the NF-kappa-B p65-p50 complex. Component of the NF-kappa-B p65-p50 complex. Homodimer; component of the NF-kappa-B p50-p50 complex. Component of the NF-kappa-B p105-p50 complex. Component of the NF-kappa-B p50-c-Rel complex. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Also interacts with MAP3K8. NF-kappa-B p50 subunit interacts with NCOA3 coactivator, which may coactivate NF-kappa-B dependent expression via its histone acetyltransferase activity. Interacts with DSIPI; this interaction prevents nuclear translocation and DNA-binding. Interacts with SPAG9 and UNC5CL. NFKB1/p105 interacts with CFLAR; the interaction inhibits p105 processing into p50. NFKB1/p105 forms a ternary complex with MAP3K8 and TNIP2. Interacts with GSK3B; the interaction prevents processing of p105 to p50. NFKB1/p50 interacts with NFKBIE. NFKB1/p50 interacts with NFKBIZ. Nuclear factor NF-kappa-B p50 subunit interacts with NFKBID. Directly interacts with MEN1. Interacts with HIF1AN.
Subcellular Location : Nucleus. Cytoplasm. Note=Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
Post-translational modifications : While translation occurs, the particular unfolded structure after the GRR repeat promotes the generation of p50 making it an acceptable substrate for the proteasome. This process 赤蘚紅號：16423-68-0is known as cotranslational processing. The processed form is active and the unprocessed form acts as an inhibitor (I kappa B-like), being able to form cytosolic complexes with NF-kappa B, trapping it in the cytoplasm. Complete folding of the region downstream of the GRR repeat precludes processing.
Phosphorylation at 'Ser-903' and 'Ser-907' primes p105 for proteolytic processing in response to TNF-alpha stimulation. Phosphorylation at 'Ser-927' and 'Ser-932' are required for BTRC/BTRCP-mediated proteolysis.
Polyubiquitination seems to allow p105 processing.
S-nitrosylation of Cys-61 affects DNA binding.
The covalent modification of cysteine by 15-deoxy-Delta12,14-prostaglandin-J2 is autocatalytic and reversible. It may occur as an alternative to other cysteine modifications, such as S-nitrosylation and S-palmitoylation.
Similarity : Contains 7 ANK repeats.
Contains 1 death domain.
Contains 1 RHD (Rel-like) domain.
Database links : UniProtKB/Swiss-Prot: P19838.2
英文名稱  Anti-NEDD8
中文名稱  泛素樣蛋白NEDD8抗體
別    名  NED8; NEDD 8; Neddylin; Neural precursor cell expressed developmentally down regulated 8; Neural precursor cell expressed developmentally down regulated gene 8; Rub1; Ubiquitin like protein Nedd 8; Ubiquitin like protein Nedd8.
濃    度  1mg/1ml
規 格  0.2ml/200μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應  Human, Mouse, Rat, Pig, Cow
產品類型  一抗   
研究領域  腫瘤 免疫學 神經生物學 信號轉導 轉錄調節因子 
蛋白分子量  predicted molecular weight: 8.5kDa
性    狀  Lyophilized or Liquid