乙二醛縮雙（鄰氨基酚）號：1149-16-2   
英文名稱：GBHA；Glyoxal-bis-(2-hydroxyanil)；Di-(o-hydroxyphenylimino)ethane；2,2′-(Ethanediylidenedinitrilo)diphenol   
其他名稱：乙二醛縮雙鄰羥苯胺；乙二醛雙(2-羥基苯胺)；鈣紅；乙二醛縮雙(鄰氨基*)；乙二醛-雙(2-羥基縮苯胺)；新鈣試劑   
號：1149-16-2   
C14H12N2O2=240.26   
級別：CP   
熔點：194～198℃   
乙醇溶解試驗：合格   
靈敏度試驗：合格   
灼燒殘渣：≤0.1%   
性狀(以下信息僅供參考)：白色或乳白色結晶性粉末。溶于甲醇、丙同和乙醇,不溶于水。新配制的溶液為無色,放置后由于分解逐漸變為黃色。熔點204℃(略分解)。有刺激性。   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)測定微量鈣、鎘、鈾和鋁。光度測定鈣、鉺、銦、鈧、釤和釔。   
保存：RT乙二醛縮雙（鄰氨基酚）號：1149-16-2存條件：
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
運輸：汽車運輸、EMS郵政快遞，申通快遞等， 款到上海3天內發貨；
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存儲：應貯存在干燥清潔避光的環境中，嚴禁與有毒物質混放，以免污染（保質期為兩年）。
乙二醛縮雙（鄰氨基酚）號：1149-16-2主要優級純、分級純和化學純3種：
（1）優級純（GR：Guaranteed reagent），又稱一級品或保證試劑，99.8%，這種試劑純度Z高，雜質含量Z低，適合于重要精密的分析工作和科學研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級試劑，純度很高，99.7%，略次于優級純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學純（CP），又稱三級試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學校一般分析工作。使用藍色（深藍色）標簽。
（4）實驗試劑（LR：Laboratory reagent），又稱四級試劑。
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translocate to the nucleus and activate transcription.
Subunit : Interacts with RELA; the interaction requires the nuclear import signal. Interacts with NKIRAS1 and NKIRAS2. Part of a 70-90 kDa complex at least consisting of CHUK, IKBKB, NFKBIA, RELA, IKBKAP and MAP3K14. Interacts with HBV protein X. Interacts with RWDD3; the interaction enhances sumoylation. Interacts (when phosphorylated at the 2 serine residues in the destruction motif D-S-G-X(2,3,4)-S) with BTRC. Associates with the SCF(BTRC) complex, composed of SKP1, CUL1 and BTRC; the association is mediated via interaction with BTRC. Part of a SCF(BTRC)-like complex lacking CUL1, which is associated with RELA; RELA interacts directly with NFKBIA. Interacts with PRMT2. Interacts with PRKACA in plaets; this interaction is disrupted by thrombin and collagen. Interacts with HIF1AN.
Subcellular Location : Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Post-translational modifications : Phosphorylated; disables inhibition of NF-kappa-B DNA-binding activity. Phosphorylation at positions 32 and 36 is prerequisite to recognition by UBE2D3 leading to polyubiquitination and subsequent degradation.
Sumoylated; sumoylation requires the presence of the nuclear import signal. Monoubiquitinated at Lys-21 and/or Lys-22 by UBE2D3. Ubiquitin chain elongation is then performed by CDC34 in cooperation with the SCF(FBXW11) E3 ligase complex, building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. The resulting polyubiquitination leads to protein degradation. Also ubiquitinated by SCF(BTRC) following stimulus-dependent phosphorylation at Ser-32 and Ser-36.
Deubiquitinated by porcine reproductive and respiratory syndrome virus Nsp2 protein, which thereby interferes with NFKBIA degradation and impairs subsequent NF-kappa-B activation.
DISEASE : Defects in NFKBIA are the cause of ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant (ADEDAID) [MIM:612132]. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. ADEDAID is an ectodermal dysplasia associated with decreased production of pro-inflammatory cytokines and certain interferons, rendering patients susceptible to infection.
Similarity : Belongs to the NF-kappa-B inhibitor family.
Contains 5 ANK repeats.
英文名稱  Anti-phospho-NFKBIA(Tyr305)
中文名稱  磷酸化IKB alpha抗體
別    名  NFKBIA(phospho Y305); Inhibitor of KB alpha; I kappa B alpha; I(Kappa)B(alpha); IkappaBalpha; IKBA; IKBalpha; IkB-alpha; MAD 3; MAD3; Major histocompatibility complex enhancer binding protein 乙二醛縮雙（鄰氨基酚）號：1149-16-2MAD3; NF kappa B inhibitor alpha; NFKBI; NFKBIA; Nuclear factor of kappa light chain gene enhancer in B cells; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha.
濃    度  1mg/1ml
規 格  0.1ml/100μg
抗體來源  Rabbit 
克隆類型  polyclonal
交叉反應  Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep
產品類型  一抗  磷酸化抗體  
研究領域  腫瘤 免疫學 信號轉導 轉錄調節因子 激酶和磷酸酶 
蛋白分子量  predicted molecular weight: 35kDa
性    狀  Lyophilized or Liquid

Similarity : Belongs to the NF-kappa-B inhibitor family.