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D-蟲(chóng)熒光素游離酸號(hào)：2591-17-5   
英文名稱：D-Luciferin；Firefly Luciferin；(S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid；4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid   
其他名稱：(S)-4,5-二氫-2-(6-羥基苯并噻唑-2-基)噻唑-4-甲酸；D-熒光素；D-冷光素   
號(hào)：2591-17-5   
C11H8N2O3S2=280.32   
級(jí)別：BR   
純度：≥98.0%   
熔點(diǎn)：201～204°C   
Maximum UV absorption：533 nm   
性狀(以下信息僅供參考)：類白色至淡黃色粉末。溶于甲醇：10mg/ml；也溶于DMSO：50mg/ml   
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)化學(xué)發(fā)光試劑   
保存：2～8℃。保質(zhì)期2年 客戶根據(jù)D-蟲(chóng)熒光素游離酸號(hào)：2591-17-5性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號(hào)、沸點(diǎn)、熔點(diǎn)、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項(xiàng)、英文名、別稱、純度、級(jí)別等情況，本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定，運(yùn)輸條件不苛刻，一般儲(chǔ)存在陰涼，干燥，通風(fēng)良好的地方，遠(yuǎn)離不相容的物質(zhì)。保持容器密閉。
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fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis.
Function : Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.
Subunit : Homooligomer; mediated by the BTB domain. Interacts with HDAC3 and HDAC4. Interacts (via BTB domain) with CUL3, PSMD7 AND RCOR1.
Subcellular Location : Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation.
Tissue Specificity : Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.
DISEASE : Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.
Similarity : Contains 1 BEN domain.
Contains 1 BTB (POZ) domain.
Database links : UniProtKB/Swiss-Prot: Q96RE7.1
英文名稱  Anti-NA
中文名稱  細(xì)胞增殖相關(guān)蛋白NA抗體
別    名  EC Rep1a; EC_Rep1a; NANO1_HUMAN; NANOS 1; Nanos homolog 1 (Drosophila); Nanos homolog 1; NA; Nos 1; NOS-1; ; OTTHUMP00000046853; Rep 1a; Rep1a.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來(lái)源  Rabbit 
克隆類型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep
產(chǎn)品類型  一抗   
研究領(lǐng)域  腫瘤 發(fā)育生物學(xué) 干細(xì)胞 
蛋白分子量  predicted molecular weight: 30kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from Human NA
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蠟切片需做抗原修復(fù)）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Nais a 292 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains one nanos-type zinc finger. Expressed at high levels in spermatogonia and present at lower levels in fetal ovaries, Na forms a complex with Pumilio 2 and functions to regulate the translation of select mRNAs, specifically via association with the 3’-UTR of its mRNA targets. Additionally, Na is required for the establishment and maintenance of germline stem cells, as it prevents their premature entry into oogenesis. The gene encoding Na maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome