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4-硝基苯基-α-D-吡喃甘露糖苷號:10357-27-4
英文名稱:4-Nitrophenyl α-D-mannopyranoside
其他名稱:4-硝基苯-α-D-吡喃甘露糖苷;對硝基苯-α-D-吡喃甘露糖苷
號:10357-27-4
C12H15NO8=301.25
級別:BR
純度:≥98%
熔點:178~183℃
比旋光度:150~166o(C=0.2,H2O)
性狀(以下信息僅供參考):白色或類白色粉末,溶于二甲基甲酰胺:50mg/ml
用途:本品僅供科研,不得用于其它用途
保存:-20℃客戶根據4-硝基苯基-α-D-吡喃甘露糖苷號:10357-27-4 性質、化學式、分子式、結構式、比重、密度、號、沸點、熔點、水溶性、MSDS、用途、作用、規格包裝、性狀、注意事項、英文名、別稱、純度、級別等情況,本產品化學性質穩定,運輸條件不苛刻,一般儲存在陰涼,干燥,通風良好的地方,遠離不相容的物質。保持容器密閉。
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產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimay involved in this process are the s4-硝基苯基-α-D-吡喃甘露糖苷號:10357-27-4 erine/threonine (Ser/Thr) protein kinases. SPAK, also known as STK39 (serine threonine kinase 39), DCHT or PASK, is a 547 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one protein kinase domain. Expressed predominay in pancreas, brain, heart, lung, liver and testis, SPAK functions as a Ser/Thr protein kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in mediating stress-activated signals. The gene encoding SPAK maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome.
Function : May act as a mediator of stress-activated signals.
Subunit : The phosphorylated form forms a complex with WNK2 (By similarity).
Subcellular Location : Cytoplasm. Nucleus. Nucleus when caspase-cleaved.
Tissue Specificity : Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis.
Post-translational modifications : Phosphorylated at Ser-309 by PRKCQ.
Similarity : Belongs to the protein kinase superfamily.
STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 protein kinase domain.
Database links : UniProtKB/Swiss-Prot: Q9UEW8.3
英文名稱 Anti-Stanniocalcin 2
中文名稱 斯鈣素2抗體
別 名 Stanniocalcin related protein; Stanniocalcin-2; Stanniocalcin-related protein; Stanniocalcin2; STC 2; STC related protein; STC-2; STC-related protein; STC2; STC2_HUMAN; STCRP.
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat
產品類型 一抗
研究領域 細胞生物 發育生物學 信號轉導 干細胞 糖蛋白
蛋白分子量 predicted molecular weight: 31kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Stanniocalcin 2
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).
Function : Has an anti-hypocalcemic action on calcium and phosphate homeostasis.
Subcellular Location : Secreted.
Tissue Specificity : Expressed in a variety of tissues including muscle, heart, pancreas, kidney, spleen, prostate, small intestine, colon and peripheral blood leukocytes.
Similarity : Belongs to the stanniocalcin family.
Database links : UniProtKB/Swiss-Prot: O76061.1
英文名稱 Anti-SNX4
中文名稱 分選連接蛋白4抗體
別 名 ATG24B; SNX 4; snx4; SNX4_HUMAN; Sorting nexin 4; Sorting nexin-4.
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