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公司提供的1,6-二磷酸果糖二鈣鹽號：6055-82-9*，貨源充足。嚴格的生產質量控制體系，包括：優級純，分析純，化學純，試劑級，基準試劑，實驗純，教學試劑，高純試劑，色譜純，光譜純，電子純。各種包裝規格，并可提供包裝定制，咨詢訂購。
1,6-二磷酸果糖二鈣鹽號：6055-82-9
英文名稱：FDPCa2；D-Fructose-1,6-diphosphate dicalcium salt；D(+)Fructofuranose 1,6-diphosphate； Harden-Young ester；Hexose diphosphate
其他名稱：1,6-二磷酸左旋糖二鈣鹽；D-果糖-1,6-二磷酸二鈣鹽；果糖-1,6-二磷酸二鈣鹽；D-果糖-1,6-二磷酸鈣鹽
號：6055-82-9
C6H10Ca2O12P2=416.24
級別：BR
含量：≥85%
鈣離子：11～16%
干燥失重：≤20.0%
性狀(以下信息僅供參考)：類白色或黃色粉末
用途：本品僅供科研，不得用于其它用途
保存：2～8℃客戶根據1,6-二磷酸果糖二鈣鹽號：6055-82-9性質、化學式、分子式、結構式、比重、密度、號、沸點、熔點、水溶性、MSDS、用途、作用、規格包裝、性狀、注意事項、英文名、別稱、純度、級別等情況，本產品化學性質穩定，運輸條件不苛刻，一般儲存在陰涼，干燥，通風良好的地方，遠離不相容的物質。保持容器密閉。
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包裝：1kg、100g、10g、250g、25g、500g、50g、5g等包裝
級別：GR級別、AR級別、CP級別、L.P.級別等

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Tissue Specificity : Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages and absent from Sertoli cells, while isoform 2 is present in both (at protein level). Expressed in the choroid plexus epithelium, isoform 1 being localized at the basolateral membrane and isoform 2 at the apical one, as well as in the subapical intracellular vesicular compartments. Differential expression of both isoforms is also observed in other brain region: isoform 1 is very abundant in the gray matter of the frontal cortex, but is not associated with neuronal cell bodies. Not detected in the white matter. In contrast, isoform 2 is associated with neuronal bodies and axons in both the gray and the white matters of the frontal cortex.
Similarity : Belongs to the organo anion transporter (TC 2.A.60) family.
Contains 1 Kazal-like domain.
Database links : UniProtKB/Swiss-Prot: Q9UIG8.3
英文名稱 Anti-SAPK3/MAPK12/p38gamma
中文名稱絲裂原活化蛋白激酶磷酸酶p38γ抗體
別    名 MAP kinase 12; MAP kinase p38 gamma; MAPK 12; Mapk12; Mitogen Activated Protein Kinase 12; ERK6; ERK 6; ERK-6; Extracellular signal-regulated kinase 6; Mitogen activated protein kinase 3; Mitogen activated protein kinase p38 gamma; Mitogen-activated protein kinase 12; Mitogen-activated protein kinase p38 gamma; MK12_HUMAN; P38 GAMMA; P38GAMMA; PRKM12; SAPK 3; SAPK3; Stress Activated Protein Kinase 3; Stress-activated protein kinase 3.
濃    度 1mg/1ml
規格 0.1ml/100μg 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat
產品類型一抗
研究領域細胞生物信號轉導細胞凋亡激酶和磷酸酶細胞粘附分子細胞分化
蛋白分子量 predicted molecular weight: 42kDa
性    狀 Lyophilized or Liquid
免疫原 KLH conjugated synthetic peptide derived from human SAPK3/MAPK12/p38gamma
亞    型 IgG
純化方法 affinity purified by Protein A
儲存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38 alpha, p38 beta and p38 gamma, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38 alpha, p38 beta and p38 gamma are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
Function : Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.
Subcellular Location : Cytoplasm. Mitochondrion. Mitochondrial when associated with SH3BP5.
Tissue Specificity : Highly expressed in skeletal muscle and heart.
Post-translational modifications : Dually phosphorylated on Thr-183 and Tyr-185, which activates the enzyme.
Similarity : Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
MAP kinase subfamily.
Contains 1 protein kinase domain.
Database links : UniProtKB/Swiss-Prot: P53778.3
英文名稱 Anti-phospho-SAPK3 (Thr183+Tyr185)
中文名稱磷酸化絲裂原活化蛋白激酶磷酸酶p38γ抗體
別    名 p-SAPK3(phospho-Thr183+Tyr185); MAP kinase 12; MAP kinase p38 gamma; MAPK 12; Mapk12; Mitogen Activated Protein Kinase 12; ERK6; ERK 6; ERK-6; Extracellular signal-regulated kinase 6; Mitogen activated protein kinase 3; Mitogen activated protein kinase p38 gamma; Mitogen-activated protein kinase 12; Mitogen-activated protein kinase p38 gamma; MK12_HUMAN; P38 GAMMA; P38GAMMA; PRKM12; SAPK 3; SAPK3; Stress Activated Protein Kinase 3; Stress-activated protein kinase 3.
濃    度 1mg/1ml
規格 0.2ml/100μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Guinea Pig
產品類型一抗磷酸化抗體
研究領域細胞生物信號轉導細胞凋亡激酶和磷酸酶細胞粘附分子細胞分化
蛋白分子量 predicted molecular weight: 42kDa
性    狀 Lyophilized or Liquid
免疫原 KLH conjugated synthesised phosphopeptide derived from human SAPK3 around the phosphorylation site of Thr183+Tyr185 [EM(p-T)G(p-Y)VV]
亞    型 IgG
純化方法 affinity purified by Protein A
儲存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
產品應用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 MAP (mitogen-activated protein) kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. p38 alpha, p38 beta and p38 gamma, also known as MAPK14, MAPK11 and MAPK12, respectively, each contain one protein kinase domain and belong to the MAP kinase family. Expressed in different areas throughout the body with common expression patterns in heart, p38 proteins use magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Via their catalytic activity, p38 alpha, p38 beta and p38 gamma are involved in a variety of events throughout the cell, including signal transduction pathways, cytokine production and cell proliferation and differentiation. The p38 proteins are subject to phosphoryation on Thr and Tyr residues, an event which is thought to activate the phosphorylated protein.
Function : Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.
Subcellular Location : Cytoplasm. Mitochondrion. Mitochondrial when associated with SH3BP5.
Tissue Specificity : Highly expressed in skeletal muscle and heart.