Membrane Target Systems are quality assured frozen membranes from cells that express recombinant or endogenous receptors.
We submit every batch of receptor to stringent quality control
testing that includes saturation radioligａnd binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPγS data is also provided for some of our Gi-coupled receptors.
Membranes are carefully prepared and ready for a variety of HTS applications, including radioligａnd binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).
Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.
Some of our receptors may be restricted for sale in specified countries. Please inquire.
規格
| 檢測目標類 | GPCR |
|---|---|
| 檢測目標類型 | Membrane preparation |
| 檢測驗證 | Binding |
| G-Alpha天然受體 | Gq/G11 |
| 宿主細胞 | CHO-K1 |
| 產品品牌名稱 | Membrane Target Systems |
| 受體類型 | Acetylcholine (Muscarinic), Muscarinic |
| 運輸條件 | 干冰 |
| 治療領域 | Central Nervous System, Cardiovascular, Gastrointestinal |
| 產品尺寸 | 400 units |
